Timolol Maleate Ophthalmic Gel Forming Solution
Timolol maleate ophthalmic gel forming solution is a non-selective beta-adrenergic receptor blocker. It works by reducing the formulation of aqueous humor (fluid in the eye), which decreases the pressure inside the eye. The gel-forming formulation transitions from a liquid to a gel upon contact with the eye surface, extending its contact time and allowing for convenient once-daily dosing.
Dosage by Body Weight
Instill one drop of the 0.25% or 0.5% solution in the affected eye(s) once daily. Invert the closed container and shake once before each use.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- Avoid use
- Tracking Notes
- Safety and efficacy have not been established in infants. Significant risk of systemic beta-blockade (e.g., bradycardia, apnea).
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- Avoid use
- Tracking Notes
- Systemic absorption poses high risks of respiratory and cardiovascular adverse effects in infants.
- Body Weight
- 8-10 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed by a specialist
- Tracking Notes
- Should only be used under strict pediatric ophthalmologist supervision. Monitor heart rate closely.
- Body Weight
- 11-15 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed by a specialist
- Tracking Notes
- Apply nasolacrimal occlusion (press inner corner of eye) for 1 to 2 minutes after instillation to minimize systemic absorption.
- Body Weight
- 16-20 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed by a specialist
- Tracking Notes
- Requires careful monitoring for asthma-like symptoms, wheezing, or slowed pulse.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | Avoid use | Safety and efficacy have not been established in infants. Significant risk of systemic beta-blockade (e.g., bradycardia, apnea). |
| 5-7 kg | Not recommended | Avoid use | Systemic absorption poses high risks of respiratory and cardiovascular adverse effects in infants. |
| 8-10 kg | Not routine | Use only if prescribed by a specialist | Should only be used under strict pediatric ophthalmologist supervision. Monitor heart rate closely. |
| 11-15 kg | Not routine | Use only if prescribed by a specialist | Apply nasolacrimal occlusion (press inner corner of eye) for 1 to 2 minutes after instillation to minimize systemic absorption. |
| 16-20 kg | Not routine | Use only if prescribed by a specialist | Requires careful monitoring for asthma-like symptoms, wheezing, or slowed pulse. |
Formulation
Purpose
Used to lower elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Generic Name
Timolol maleateBranded Drug Names
Timolol Maleate Ophthalmic Gel Forming Solution is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.